Novel two-dimensional materials based bio-nanophotonics
Carbon nanomaterials for phototherapy
Phototherapy attracts increasing interest for broad bio-applications due to its noninvasive and highly selective nature. Owing to their good biocompatibility, unique optoelectronic properties and size/surface effects, carbon nanomaterials show great promise …
Two-dimensional transition metal carbides and nitrides (MXenes) based biosensing and molecular imaging
As a “star material”, 2D transition metal carbides and/or nitrides (MXenes) have tremendous potential applications in biosensor development and molecular imaging. MXenes have a lot of advantages due to their large specific surface, excellent electrical …
Two-dimensional photonic MXene nanomedicine
Two-dimensional (2D) transition metal carbides and nitrides (MXenes) with fascinating physicochemical properties, ultrathin lamellar structure, high specific surface area, and excellent biocompatibility have been extensively explored in biomedical …
Two-dimensional nanostructures based ‘-onics’ and ‘-omics’ in personalized medicine
With the maturing techniques for advanced synthesis and engineering of two-dimensional (2D) materials, its nanocomposites, hybrid nanostructures, alloys, and heterostructures, researchers have been able to create materials with improved as well as novel …
Emerging nanophotonic biosensor technologies for virus detection
Highly infectious viral diseases are a serious threat to mankind as they can spread rapidly among the community, possibly even leading to the loss of many lives. Early diagnosis of a viral disease not only increases the chance of quick recovery, but also …
Three birds with one stone: oxygen self-supply engineering palladium nanocluster/titanium carbide hybrid for single-NIR laser-triggered synergistic photodynamic-photothermal therapy
As a key branch of the cross-discipline biophotonics, phototherapy, including photodynamic therapy (PDT), and photothermal therapy (PTT), is promising in biomedicine and visible light-driving PDT has been applied to clinical treatment. However, extensive …
Oxygen-supplied electrotherapy for enhanced photodynamic synergistic therapy overcomes hypoxia tumor microenvironment
Photodynamic therapy (PDT) has lately been identified as a promising anticancer method and gained tremendous interest due to its controllability, non-invasive nature, and negligible side effects. Nevertheless, the development of PDT is hampered by two …
NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy
Photodynamic therapy (PDT) for hypoxic tumors has attracted wide attention owing to its noninvasiveness, easy maneuverability, and instantaneity. However, hypoxia in tumors and penetration depth of conventional ultraviolet light has greatly weakened its …
Highly active selenium nanotherapeutics combined with metformin to achieve synergistic sensitizing effect on NK cells for osteosarcoma therapy
NK cells-based cancer therapy combined with chemotherapeutic drugs for the treatment of tumors can enhance the immunosensitivity of NK cells, increase the expression of NK cell receptors, and eventually boost the killing effect of NK cells on cancer cells. …
Self-powered broadband photodetector based on MoS_2/Sb_2Te_3 heterojunctions: a promising approach for highly sensitive detection
Topological insulators have shown great potential for future optoelectronic technology due to their extraordinary optical and electrical properties. Photodetectors, as one of the most widely used optoelectronic devices, are crucial for sensing, imaging, …
Fluorescein-derived carbon dots with chitin-targeting for ultrafast and superstable fluorescent imaging of fungi
Fluorescence microscopy based on fluorochrome has been rapidly developed as the candidate for morphological identification of pathogenic fungi over recent years, offering superior rapidity and efficacy over traditional culture methods. However, the intrinsic …
A pH-sensitive liposomal co-delivery of fingolimod and ammonia borane for treatment of intracerebral hemorrhage
Intracerebral hemorrhage (ICH) is one of the most devastating types of stroke. This study aims to develop a new drug carrier with hematoma-specific response and high property. pH-sensitive liposomes (PSL) were developed. Fingolimod with ammonia borane were …
Exploring magneto-optic properties of colloidal two-dimensional copper-doped CdSe nanoplatelets
Transition-metal-doped semiconductor nanocrystals have received significant attention because of their attractive features deeming them invaluable in various technological fields including optoelectronics, bio-photonics, and energy conversion, to name a few. …
Nanoparticle-on-mirror pairs: building blocks for remote spectroscopies
Surface-enhanced spectroscopies, such as surface-enhanced Raman scattering (SERS), fluorescence (SEF), circular dichroism, etc., are powerful tools for investigating nano-entities with high sensitivities. Owing to the giant local electric field confined in a …
Mesoporous biophotonic carbon spheres with tunable curvature for intelligent drug delivery
Mesoporous carbon spheres (MCSs) are widely used in the field of pollutants adsorption, energy storage and various biomedicine applications such as targeted delivery vector, phototherapy sensitizers, bioimaging contrast agents, etc. Current synthetic …
Manganese-functionalized MXene theranostic nanoplatform for MRI-guided synergetic photothermal/chemodynamic therapy of cancer
Two-dimensional transition metal carbides and nitrides (MXenes) nanosheets with high photothermal conversion efficiency as well as photothermal stability can efficiently generate remarkable hyperthermia for photothermal therapy (PTT) of cancer. However, …
Copper decorated Ti_3 C_2 nanosystem with NIR-II-induced GSH-depletion and reactive oxygen species generation for efficient nanodynamic therapy
Nanodynamic therapy (NDT) based on reactive oxygen species (ROS) production has been envisioned as an effective cancer treatment. However, the efficacy is limited by the hypoxia, insufficient hydrogen peroxide conversion, and high glutathione (GSH) levels in …